Laparoscopic diagnosis and treatment of urinary tract endometriosis in a referral center

Laparoscopic diagnosis and treatment of urinary tract endometriosis in a referral center

Maria Manzone1, Matteo CeccarelloOrcid, Francesco Bruni1, Giovanni RoviglioneOrcid, Roberto ClariziaOrcid, Daniele MautoneOrcid, Giuseppe CaleffiOrcid Alberto MolinariOrcid Marcello Ceccaroni1 – Orcid

1 – Department for the Protection of Women’s Health and Quality of Life, ISSA International School of Surgical Anatomy, IRCCS Sacro Cuore Don Calabria Hospital, Negrar, Verona

Corresponding Author: Maria Manzone

maria.manzone@sacrocuore.it


DOI: 10.53146/lriog1202133

Abstract

The diagnosis of extra-genital Deep Endometriosis is very frequent in referral centers. The urinary tract represents the second most affected extra-genital site. Bladder Endometriosis is defined as Deep Endometriosis infiltrating the detrusor muscle, partially or fully. Ureteral endometriosis is subdivided into intrinsic and extrinsic form, with an obstruction to the spread of parametric Deep Endometriosis. Patients often come to a referral center after a long period of lack of medical therapy and / or several incomplete surgeries. While patients with Bladder Endometriosis are symptomatic, Ureteral Endometriosis is more often low / asymptomatic, leading to progressive and silent renal failure. Having a systematic model of pre-operative diagnosis, an intra-operative evaluation plan using the cooperation of a multi-disciplinary team in a referral center, represents the solution able to reducing the consequences of late diagnosis and offer precise surgical treatment. A complete ultrasound scan (pelvic and abdominal) performed by an experienced operator could allow the diagnosis; second level exams (Magnetic Resonance Imaging, CT urograhy, scintigraphy) can help to confirm and define it. The treatment of Bladder Endometriosis depends on various factors (symptoms, extent of the disease, age of the patients, childbearing desire). In cases of refractory to medical therapy, laparoscopic surgery is the treatment that leads to more complete cure, long-term relief of symptoms and low relapse rates. Any ureteral stenosis caused by an intrinsic lesion requires a ureteral resection. Ureterolysis is the procedure for removing extrinsic ureteral lesions that do not cause direct stenosis, preventing disease progression. An intraoperative evaluation of the ureters after ureterolysis is mandatory to determine the surgical outcome. The laparoscopic nerve-sparing eradication of Deep Endometriosis of the urinary tract is the way to provide good results in terms of symptoms’ control and relapses, an improvement of quality of life with a low post-operative complications rate. The possibility in a reference center to make use of a multidisciplinary team is essential to be the best surgical strategy before and intraoperatively.

Keywords: deep endometriosis; bladder endometriosis; ureteral endometriosis; partial cystectomy; uretero-neocystostomy.


Available in LRIOG Nr.3 – 2021

e-ISSN: 1824-0283


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Adnexal surgery “fertility sparing” in deep endometriosis

Adnexal surgery “fertility sparing” in deep endometriosis

Anna Katarzyna StepniewskaOrcid, Giulia Mantovani1, Chiara Signori1, Maria Manzone1, Silvia BaggioOrcid, Paola De MitriOrcid, Marcello CeccaroniOrcid

1 – Department for the Protection of Women’s Health and Quality of Life, ISSA International School of Surgical Anatomy, IRCCS Sacro Cuore Don Calabria Hospital, Negrar, Verona

Corresponding Author: Anna Katarzyna Stepniewska

stepniewska.anna@gmail.com


DOI: 10.53146/lriog1202132

Abstract

Adnexal surgery in deep endometriosis represents a significant clinical problem because the patients who suffer from it are typically of childbearing age and often, in addition to aiming for the improvement of painful sym- ptoms, have a desire for pregnancy. Endometriosis can cause infertility and the surgical removal of the disease implies a good chance of conception; at the same time surgery, in particular of endometriomas, involves the risk of a reduction in the ovarian reserve, up to its extreme consequence represented by premature menopause. For this reason, the indications for surgery must be evaluated very carefully and accompanied by an appropriate instrumental study that allows for an adequate surgical procedure; all this, in order to radically remove the disease and not expose the patient to a high risk of recurrence resulting in subsequent surgical gestures and a consequent further reduction of the ovarian reserve. Histological, anatomical aspects and hints on surgical instrumentation are presented, all useful for choosing the most appropriate surgical approach. The various traditional and innovative surgical techniques are also discussed and other additional procedures useful to reduce the risk of decreased ovarian reserve and postoperative adhesions are described.

Keywords: deep endometriosis; laparoscopic surgery; ovarian reserve; fertility.


Available in LRIOG Nr.3 – 2021

e-ISSN: 1824-0283


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Epidemiology and social impact of endometriosis today

Epidemiology and social impact of endometriosis today

Silvia BaggioOrcid, Giulia Mantovani1, Paola De MitriOrcid, Matteo CeccarelloOrcid, Maria Manzone1, Marcello Ceccaroni1– Orcid

1 – Department of Obstetrics and Gynecology, Gynecological Oncology and Mini-Invasive Pelvic Surgery, International School of Surgical Anatomy, IRCCS “Sacro Cuore – Don Calabria” Hospital, Negrar di Valpolicella, Verona

Corresponding author: Silvia Baggio

silvia.baggio@sacrocuore.it


DOI: 10.53146/lriog1202128

Abstract

Endometriosis is a chronic, persistent, recurrent pelvic disease that can cause debilitating symptoms and infertility or be completely asymptomatic. It is a very common disease among women of childbearing age, with a prevalence of around 2% in the low-risk population, from more than 40% in women with chronic pelvic pain and up to 50-60% in infertile women. It is believed that 176 million are the women affected worldwide, but the true prevalence rates are not fully known yet, mainly because the symptoms are often underestimated by primary care doctors and gynecologists, causing an average diagnostic delay of about 4-6 years. This delay is often the cause of an irrecoverable impairment of the quality of life of women, both physically, psychically and socially /relationally, as well as of an important loss of productivity and health costs soaring, making Endometriosis deserve the title of “social disease”. Understanding Endometriosis and its prevalence and improving the knowledge of its risk factors could help physicians to promptly recognize it or at least suspect it, and therefore direct the affected women to Specific Referral Centers, thus allowing an early taking charge with subsequent benefit for the single and for the society.

Keywords: endometriosis; epidemiology; burden; quality of life; costs; diagnostic delay.


Available in LRIOG Nr.3 – 2021

e-ISSN: 1824-0283


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